Giuliana Rancic weight loss sparks concern at E! 2013 Upfront in New York

Giuliana Rancic appears to have lost even more weight sparking concern at the E! 2013 Upfront event held at the Manhattan Center in New York on Monday.

Giuliana Rancic, 38, chose a slinky black dress which did little to hide her shrinking frame and sinewy limbs.

When the Fashion Police host turned to the side to pose for cameras, her waist looked miniscule.

Giuliana Rancic paired the long-sleeved frock with matching patent court shoes, a statement white necklace and lots of vampish red lipstick.

It is certainly not the first time Giuliana Rancic’s thin figure has caused worry and she famously was involved in a “skinny war” with LeAnn Rimes back in 2011.

Giuliana Rancic was also forced to defend reports that her infertility was caused from her being skinny.

Her fellow Fashion Police host Kelly Osbourne was also in attendance, dressed in a matronly navy dress with white ruffled collar.

A slew of other E! stars were in attendance, including Chelsea Handler, Ryan Lochte, Kevin Jonas and, of course, the Kardashians.