The Republican nominee released the letter following a recent physical examination by Dr. Harold N. Bornstein.
Donald Trump, 70, is listed as 6ft 3in and weighing 236lb.
The letter comes as Hillary Clinton returns to the campaign trail after time off with pneumonia, appearing briefly to reporters.
Boarding a plane in White Plains, New York, Hillary Clinton spoke to journalists as she flew to North Carolina to hold a rally, her first campaign event since the weekend.
Both Donald Trump and Hillary Clinton have faced public scrutiny over transparency about the state of their health.
“He takes a lipid lowering agent (rosuvastatin) and a low dose aspirin,” the letter said.
“He does not use tobacco products or alcohol.”
Donald Trump’s weight and height give him a body mass index of 29.5, according to US measurements, which is within the “overweight” range but close to the “obese” mark at 30.0.
The Republican discussed his health with talk-show host Dr. Mehmet Oz in a taped interview, which is set to air on September 15.
Donald Trump first revealed the letter, which is dated September 13, in his appearance on The Dr. Oz Show.
“I feel as good today as I did when I was 30,” Donald Trump said on the show, according to a clip.
Dr. Harold Bornstein, a gastroenterological specialist at Lenox Hill Hospital in New York, has cared for Donald Trump since 1980, according to the letter.
The note continues to detail parts of Donald Trump’s medical record, including that he was only in hospital once at age 11 for an appendectomy.
Although the letter provides some insight, it does not include Donald Trump’s detailed medical history.
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