The as-yet-untitled film will come 11 years after the most recent Indiana Jones movie, 2008’s Kingdom of the Crystal Skull.
Harrison Ford and Steven Spielberg are teaming up for the new movie.
They first worked together on Indiana Jones movie, Raiders of the Lost Ark, in 1981.
Kathleen Kennedy and Frank Marshall are to produce the new film.
In the first outing, archaeologist Indiana Jones raced around the world to find the Ark of the Covenant before it fell into the hands of the Nazis.
It was followed three years later by Indiana Jones and the Temple of Doom, with Indiana Jones and the Last Crusade coming in 1989.
Harrison Ford, also known for his work as Han Solo in the Star Wars movies, will be 77 when the new installment arrives in cinemas.
The first four movies have made nearly $2 billion at the box office so far.
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