Entrances to Jabal Mukaber, a district where three men accused of killing three Israelis on October 13 came from, have been blocked by police on October 14.
The Israeli military also deployed hundreds of soldiers to assist.
Later, police said they had shot dead a man who attempted to stab a guard on the edge of Jerusalem’s Old City.
Since the beginning of October, seven Israelis have been killed and dozens wounded in shooting and stabbing attacks, the Israeli authorities say.
At least 30 Palestinians have also been killed, including assailants, and hundreds have been injured, according to the Palestinian health ministry.
On October 13, Israel’s security cabinet authorized police to close or surround “centers of friction and incitement” in Jerusalem.
It also announced that the homes of Palestinians who attacked Israelis would be demolished within days and never rebuilt, and that their families’ right to live in Jerusalem would be taken away.
On October 14, a police spokeswoman told the AFP news agency that checkpoints were being set up at “the exits of Palestinian villages and neighborhoods in East Jerusalem”.
Israeli newspapers later reported that several entrances to Jabal Mukaber had been blocked by police, with neither people nor vehicles allowed in or out. Several more areas were expected to be closed off by the end of the day.
Human Rights Watch warned that locking down parts of East Jerusalem would “infringe upon the freedom of movement of all Palestinian residents rather than being a narrowly tailored response to a specific concern”.
“The checkpoints are a recipe for harassment and abuse,” said Sari Bashi, the group’s Israel/Palestine country director, in a statement.
Meanwhile, the Israeli military said it was preparing to deploy six companies to assist police. Three hundred soldiers are already providing additional security under police command.
The security cabinet’s decisions were made after the bloodiest day in Jerusalem since the latest wave of unrest began in early October.
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