The Jamaican was out quicker and opened an unassailable lead over the first 100m before coming away down the straight and jabbing his thumbs at his chest as he crossed the line.
His 19.55 seconds was the fastest in the world this year, his speed and peerless championship class too good for American Justin Gatlin, whose 19.74 was well outside his season’s best.
Usain Bolt, 29, who will also compete in the 4x100m relay, said: “It means a lot to me.
“I’m happy to be a 10-time World Championships gold medalist, especially when people have been saying I would lose.
“I had the utmost confidence. As long as my coach is confident, I’m super confident.
“The British people give me a lot of love and I will continue running fast.”
South Africa’s Anaso Jobodwana set a national record of 19.87, with Panama’s Alonso Edwards three thousands of a second behind in fourth.
Justin Gatlin, twice banned for doping, had run more than two tenths of a second faster than any other man in the field this year, and almost half a second quicker than Usain Bolt.
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