The White House said President Barack Obama will host the royal couple in the Oval Office on March 19.
Charles and Camilla will be in the US from March 17 to March 20 to “promote the UK’s partnership with the United States”, Clarence House said.
They will also mark the Magna Carta’s 800th anniversary during their trip.
Other parts of their tour will include a tour of Mount Vernon – home of America’s first president, George Washington – and a visit to Louisville, Kentucky, home city of legendary boxer Muhammad Ali.
While in Washington DC, the Prince of Wales will mark the Magna Carta’s anniversary during a visit to the National Archives.
Prince Charles will view the Charters of Freedom documents and the 1297 version of the Magna Carta, which is embodied in the American Bill of Rights and the Constitution.
He will also receive an award for “exceptional leadership in conservation” from the International Conservation Caucus Foundation.
Also in Washington DC, the prince and duchess will visit the Armed Forces Retirement Home, set in the same grounds as the Lincoln Cottage, where it is believed Abraham Lincoln wrote the last draft of the Emancipation Proclamation.
The Duchess of Cornwall, who has regularly raised awareness about rape victims, will carry out several solo engagements, including visiting the District of Columbia’s assault response team.
This is a coalition of 12 public and private community agencies which works to prevent assault and help victims of such crimes.
Camilla will visit a food literacy project for young people at a local farm while in Louisville, which will be where the couple ends their trip.
Prince Charles visited the Oval Office in 2011 to discuss energy and environmental issues with President Barack Obama.
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