The commemoration will be held at the site in southern Poland where 1.1 million people, most of them Jews, were killed between 1940 and 1945.
It is expected to be the last major anniversary event that survivors are able to attend in numbers. This year, about 300 survivors have gathered for the event.
Heads of state and representatives from many wartime Allies will be present.
Events include the laying of a wreath, a church service, and the lighting of candles at a memorial in the former death camp of Birkenau, which was part of the Auschwitz complex.
Auschwitz-Birkenau was liberated by the Red Army of the Soviet Union on January 27, 1945.
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