It is the first time for modern Spain to put a royal in the dock to face trial.
Infanta Cristina’s husband, Inaki Urdangarin, is accused of embezzling millions in public funds with a former business partner.
Princess Cristina and Inaki Urdangarin deny wrongdoing.
Prosecutors in Palma, Majorca, say Inaki Urdangarin’s sports foundation misused public money.
It is alleged that €5.6 million ($7.5 million) of public money went missing from the Noos Institute, a charitable sports foundation, when Inaki Urdangarin was in charge of it.
Princess Cristina, 49, is under suspicion over €2.6 million of that money. She is the sister of King Felipe VI, and youngest daughter of the former king, Juan Carlos.
The allegations relate to business affairs between 2007 and 2008.
Inaki Urdangarin and his then business partner, Diego Torres, allegedly used the Noos Institute to organize events for the regional governments of Valencia and the Balearic Islands at hugely inflated prices.
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