The movie easily topped the chart, which saw Transformers: Age of Extinction slip to second with $16.5 million.
The Apes epic also picked up another $31 million from international markets.
Set 10 years after 2011’s Rise of the Planet of the Apes, the sequel follows the battle for dominance between humans and intelligent apes.
Andy Serkis has reprised his performance-capture role as Caesar, the ape who leads his species after encountering a colony of humans who survive a deadly virus.
He also famously played Gollum in the Lord of the Rings and Hobbit movies, which also used performance capture, which electronically tracks an actor’s movements and expressions so they can be translated into computer generated imagery (CGI).
Directed by Cloverfield’s Matt Reeves, Dawn of the Planet of the Apes also stars Gary Oldman, Keri Russell and Jason Clarke.
The sequel opened more strongly than its predecessor, which took $54.8 million during its opening weekend.
A second sequel to be directed by Matt Reeves is already in the works to further extend the franchise which first began with 1968’s Planet of the Apes, based on Pierre Boulle’s French novel.
Four movies followed in the 1970s, as well as a critically panned 2001 reboot by Tim Burton.
Elsewhere on the chart, Melissa McCarthy and Susan Sarandon comedy Tammy – about a fast food worker who gets fired and takes her hard-drinking grandmother on a road trip – was at three with $12.9 million.
Sequels 22 Jump Street and How to Train Your Dragon 2 took the fourth and fifth spots with $6.7 million and $5.9 million respectively.
North American box office Top 5:
Source: Rentrak
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