A study in the journal JAMA found people with mild to moderate Alzheimer’s disease on high doses of vitamin E had a slower rate of decline than those given a dummy pill.
They were able to carry out everyday tasks for longer and needed less help from carers, say US researchers.
The Alzheimer’s Society said the dosage was very high and might not be safe.
In the study, 613 people with mild to moderate Alzheimer’s disease received either a daily dose of vitamin E, a dementia drug treatment known as memantine, a combination of vitamin E and memantine, or placebo.
Changes in their ability to carry out everyday tasks – such as washing or dressing – were measured over an average of two years.
The study found participants receiving vitamin E had slower functional decline than those receiving placebo, with the annual rate of decline reduced by 19%.
Those on vitamin E (also known as alpha tocopherol) also needed less help from carers.
“These findings suggest that alpha tocopherol is beneficial in mild to moderate Alzheimer’s disease by slowing functional decline and decreasing caregiver burden,” said a team led by Dr. Maurice Dysken of Minneapolis VA Health Care System.
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