In the letter to the Harvard Crimson, Bo Guagua said he was “deeply concerned” about his family.
Bo Guagua, 24, denied he was a bad student, citing his grades, and set out how his education had been funded.
The whereabouts of his father are unknown and his mother is being investigated in connection with the death of British national Neil Heywood.
The removal of Bo Xilai, who was once tipped for China’s highest office, has become the country’s biggest political scandal in years.
Since Chinese authorities announced he had been sacked from his political positions earlier this month a stream of reports concerning him and his family have emerged.
Some reports have focused on the reportedly extravagant and well-funded lifestyle of his son, Bo Guagua, who is currently studying at Harvard University after completing his degree at Oxford.
Since the allegations against his family emerged, Bo Guagua has kept a low profile. But in the letter published on Tuesday on the Harvard Crimson website, he said he wanted to address recent media reports.
“I am deeply concerned about the events surrounding my family, but I have no comments to make regarding the ongoing investigation,” Bo Guagua wrote.
“It is impossible to address all of the rumors and allegations about myself, but I will state the facts regarding some of the most pertinent claims.”
His education, Bo Guagua said, had been funded by scholarships and his mother’s earnings as a lawyer. His grades, which he cited, had earned him his university places.
While at Oxford University he had taken part in social events and extra-curricular activities – but these were a “regular feature of social life” at university.
In China, Bo Guagua said, he had never participated in a for-profit business. And he did not drive a Ferrari, he said, addressing a specific claim.
The Wall Street Journal reported last year that Bo Guagua had arrived at then US ambassador to China Jon Huntsman’s residence to pick up his daughter in a red Ferrari.
“I understand that at the present, the public interest in my life has not diminished,” Bo Guagua said.
“However, I wholeheartedly request that members of the press kindly refrain from intruding into the lives of my teachers, friends and classmates.”
Benjamin Samuels, president of Harvard Crimson, said the statement came from Bo Guagua’s Harvard’s Kennedy School e-mail address, and that the team had then spoken to him via telephone to verify the statement was his.
Allegations against his parents emerged earlier this year after Chongqing’s police chief, Wang Lijun, fled to the US consulate in an apparent bid to seek asylum.
Chinese state media said Wang Lijun, who was once Bo Xilai’s right-hand man, had information concerning the death of British businessman Neil Heywood, who died in a Chongqing hotel in November 2011.
Bo Xilai’s wife, Gu Kailai, is now being investigated in connection with the case, amid unconfirmed media reports that Neil Heywood was poisoned.
Bo Xilai has not been seen since his sacking was announced. It comes with China due to begin its once-in-a-decade leadership change in October.
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