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Dannielynn Birkhead played up the chance to throw on her best new dress as she and her father Larry attended the premiere for The Smurfs 2 in Los Angeles on Sunday.

Dannielynn Birkhead, 6, dolled herself up for the film in a grey chevron frock with blue and yellow accents, complete with a picture of her favorite smurfette on the centre.

And always eager to play a part in his daughter’s well being was father Larry Birkhead, who dressed to match in a grey, yellow and blue T-shirt and jeans.

Larry Birkhead was granted custody of the youngster after her mother Anna Nicole Smith passed away from a drug overdose in 2007.

Dannielynn Birkhead is reportedly set to inherit her mother’s fortune, which got a $49 million boost as part of oil tycoon J. Howard Marshall’s estate.

Dannielynn Birkhead and her father Larry attended the premiere for The Smurfs 2 in Los Angeles

Dannielynn Birkhead and her father Larry attended the premiere for The Smurfs 2 in Los Angeles

Anna Nicole Smith and J. Howard Marshall were married in 1994 when she was just 26, and he was 89.

J. Howard Marshall died a year later.

Meanwhile, Dannielynn Birkhead is growing up to be the spitting image of her mother, who was aged just 39 when she was found dead in a Florida hotel room.

Her father Larry Birkhead, who was forced to establish paternity in a suit against Anna Nicole Smith’s then partner and lawyer Howard K. Stern, seems to have done an excellent job raising his daughter by himself.

“I see her mom in everything she does,” Larry Birkhead told UsWeekly.

Dannielynn Birkhead recently appeared in an advertising campaign for Guess Kids.

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Britney Spears’ sons Sean Preston, seven, and Jayden James, six, make their very first cameo appearances in the video clip for the singer’s new song Ooh La La, which is set to be released on VEVO on Thursday.

Britney Spears, 31, shared a sneak peek snap of the video with her fans on Wednesday on Twitter.

In the image, the singer is seen sitting in a cinema eating popcorn with her sons.

“Omg. How CUTE are my boys?!  Video premieres Thursday on @VEVO at noon ET! #OohLaLaThursday” Britney Spears she wrote in an accompanying caption.

The princess of pop shows off her toned legs in a pair of tiny shorts paired with a light pink shirt in the image.

Britney Spears' sons Sean Preston and Jayden James make their very first cameo appearances in the video clip for her new song Ooh La La

Britney Spears’ sons Sean Preston and Jayden James make their very first cameo appearances in the video clip for her new song Ooh La La

Meanwhile, her boys, who could actually pass as twins, both wear checked shirts in different colors, with Jayden in a blue version and Sean in a red and black variety.

Later in the day she also posted some moving images of the clip, with one frame showing the singer wearing a red dress and holding onto her boys’ hands.

Last month, Britney Spears debuted her new single Ooh La La, which was written for the Smurfs 2 movie soundtrack.

“I have always loved the Smurfs as a kid and now my boys are the biggest Smurfs fans ever,” she  said in a statement.

“I wanted to surprise them with a song in the movie. I know they’ll think it’s Smurftastic!”

Sean Preston and Jayden James are Britney Spears’ sons from her marriage to Kevin Federline.

Britney Spears says her boys were the consummate professionals on the day that they shot the video.

“My oldest son, Preston, was right on cue every time they would tell him to do something in the video,” Britney proudly told Ryan Seacrest on his KIIS radio show.

“They play themselves. But when we did the actual shoot of the video, I didn’t see them.

“I was in hair and make-up, so later on I got to see what they actually did on camera – and it was adorable!”

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The extraordinary story of Appalachia’s “Blue Family” began back to the early 1800’s, when an isolated family from eastern Kentucky – who can trace their roots back to a French orphan – started producing children who were blue.

As a result of a coincidental meeting of recessive genes, intermarriage and inbreeding, members of the Fugate family were born with a rare condition that made them visibly discolored.

The mystery behind the astonishing picture of the Fugates, which has been baffling people for years, appears to have finally been solved.

The story began when Martin Fugate, a French orphan, settled on the banks of eastern Kentucky’s Troublesome Creek to claim a land grant in the early 19th century.

Martin Fugate married a red-haired American named Elizabeth Smith – who had a very pale complexion – and their union formed a genetic mutation that resulted in their descendants being born with blue skin.

Looking at the portrait, they appear to have been either Photoshopped or made up to mimic characters from children’s cartoon The Smurfs, but science proves that the condition is in fact real.

Fugate family developed a rare skin discoloration as a result of a coincidental meeting of recessive genes, intermarriage and inbreeding

Fugate family developed a rare skin discoloration as a result of a coincidental meeting of recessive genes, intermarriage and inbreeding

Called methaemoglobinaemia (commonly known as met-H), the condition reduces the individual’s ability to carry oxygen in their blood. As a result, their blood is darker than the color typically found running through people’s veins.

Because the Fugate family lived in such an isolated part of the Kentucky, they intermarried with a neighboring family for generations which led to a relatively “pure” gene pool where the met-H gene appeared much more frequently.

The family was first discovered in 1958 when one of the blue men, Luke Combs, who was a descendant of another branch of the Fugate family, took his white wife to the University of Kentucky Hospital and doctors paid more attention to him than his wife.

“Luke was just as blue as Lake Louise on a cool summer day,” Dr. Charles H. Behlen II told the Tri-City Herald in 1974.

Aside from the stark discoloration of the carrier’s skin, there are no serious problems associated with the disease.

In 1980, a counter-intuitive solution was discovered where the blue person drinks a chemical-filled solution that is itself blue. This then turns the carrier’s blood into a “normal” red hue which is then reflected in a change in skin tone.

Because of the dispersion of fluids, the solution only lasts for about a day so the carrier would have to drink a serving every day.

As eastern Kentucky has become vastly more populated than the early 19th century, and as more genes are married into the Fugate family tree, there were far fewer children born with the condition.

That said, the recessive met-H gene lingers to this day, but it is statistically insignificant now.

“They weren’t sick; it was just the way they look,” said nurse Ruth Pendergrass in the Tri-City Herald article.

“They’re normal people – they’re good people.”

How Met-H darkens blood?

The methaemoglobinaemia condition, or “met-H”, reduces someone’s ability to carry oxygen in the blood, leaving it darker than the color typically found in veins.

The Fugate family intermarried with a neighboring family for generations, which led to a relatively “pure” gene pool, often including the met-H gene.

But as Kentucky became more populated and more genes came into the Fugate family tree, there were far fewer children born blue.

The gene is still around today but has now become statistically insignificant and there are no serious medical problems associated with it.