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Wuhan, the Chinese city where the coronavirus pandemic began, has partially re-opened after more than two months of isolation.

Crowds of passengers were pictured arriving at Wuhan train station on March 28.

According to reports, people are being allowed to enter but not leave.

Wuhan, the capital of Hubei province, saw more than 50,000 coronavirus cases. At least 3,000 people in the province died from the disease.

However, numbers have fallen dramatically, according to China’s figures. On March 28, the state reported 54 new cases emerging the previous day – which it said were all imported.

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As it battles to control cases coming from abroad, China has announced a temporary ban on all foreign visitors, even if they have visas or residence permits. It is also limiting Chinese and foreign airlines to one flight per week, and flights must not be more than 75% full.

The new coronavirus is thought to have originated in a seafood market in Wuhan that “conducted illegal transactions of wild animals”.

Wuhan’s 11 million residents have been shut off from the rest of the world since the middle of January, with roadblocks around the outskirts and drastic restrictions on daily life.

However, roads reopened to incoming traffic late on March 27, according to Reuters.

State media said the subway was open from March 28 and trains would be able to arrive at the city’s 17 railway stations.

All arrivals in Wuhan have to show a green code on a mobile app to prove that they are healthy.

Officials say restrictions on people leaving Wuhan will be lifted on April 8, when domestic flights are also expected to restart.

The new coronavirus emerged in China in December 2019 and more than 3,300 people there have died from the infection – but both Italy and Spain now have higher death tolls.

It is now battling to control a wave of imported cases as infections soar abroad.

This so-called “second wave” of imported infections is also affecting countries like South Korea and Singapore, which had been successful in stopping the spread of disease in recent weeks.

Meanwhile, the virus continues to spread rapidly in other countries around the world.

Nearly 600,000 infections have been confirmed globally and almost 28,000 deaths, according to figures collated by Johns Hopkins University.

Chinese health officials have released the first details of more than 44,000 cases of new coronavirus, Covid-19, in the largest study since the outbreak began.

Data from the Chinese Centre for Disease Control and Prevention (CCDC) finds that more than 80% of the cases have been mild, with the sick and elderly most at risk.

The research also points to the high risk to medical staff.

On February 18, a hospital director in the city of Wuhan died from the virus.

Liu Zhiming, 51, was the director of the Wuchang Hospital in Wuhan – one of the leading hospitals in the virus epicenter. He is one of the most senior health officials to die so far.

Hubei, whose capital is Wuhan, is the worst affected province in China.

The report by the CCDC shows the province’s death rate is 2.9% compared with 0.4% in the rest of the country.

The findings put the overall death rate of the coronavirus at 2.3%.

China’s latest official figures released on February 18 put the overall death toll at 1,868 and 72,436 infections.

Officials reported 98 new deaths and 1,886 new cases in the past day, with 93 of those deaths and 1,807 infections in Hubei province – the epicenter of the outbreak.

According to Chinese authorities, more than 12,000 people have recovered.

The study, published in the Chinese Journal of Epidemiology on February 17, looked at more than 44,000 confirmed cases of Covid-19 in China as of February 11.

While the results largely confirm previous descriptions of the virus and patterns of infection, the study includes a detailed breakdown of the 44,672 confirmed cases across all of China.

The study finds that 80.9% of infections are classified as mild, 13.8% as severe and only 4.7% as critical. The number of deaths among those infected, known as the fatality rate, remains low but rises among those over 80 years old.

Looking at the sex ratio, men are more likely to die (2.8%) than women (1.7%).

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The research also identifies which existing illnesses put patients at risk. It puts cardiovascular disease at number one, followed by diabetes, chronic respiratory disease and hypertension.

Pointing out the risk to medical staff, the study says that a total of 3,019 health workers have been infected, 1,716 of which were confirmed cases. Five had died by February 11, which was the last day of data included in the research.

On February 13, China broadened its definition of how to diagnose people, including “clinically diagnosed cases” which previously were counted separate from “confirmed cases”.

Looking forward, the study finds that “the epidemic curve of onset of symptoms” peaked around January 23-26 before declining up to February 11.

It suggests that the downward trend in the overall epidemic curve could mean that “isolation of whole cities, broadcast of critical information  (e.g., promoting hand washing, mask wearing, and care seeking) with high frequency through multiple channels, and mobilization of a multi-sector rapid response teams is helping to curb the epidemic”.

The authors also warn that with many people returning from a long holiday, the country “needs to prepare for the possible rebound of the epidemic”.

China’s response to the new coronavirus has seen the lockdown of Wuhan – the largest city in Hubei – and the rest of the province as well as severe travel restrictions on movements across the country.

A public health emergency has been declared in the US over the spread of the coronavirus and said it would deny entry to any foreign nationals who have visited China in the past two weeks.

According to authorities, US citizens returning from Hubei province, where the outbreak started, will be quarantined for two weeks.

Nearly 10,000 cases of the new virus have been confirmed, most of them in China, since it emerged in December.

More than 100 cases have been reported outside China, in 22 countries.

On January 31, Beijing said the death toll had risen by 45 to 258 – all of them in China and 249 in Hubei.

Earlier, it emerged that the number of new coronavirus cases worldwide had overtaken that of the SARS epidemic, which spread to more than two dozen countries in 2003.

There were around 8,100 cases of SARS – severe acute respiratory syndrome – during the eight-month outbreak. In total, 774 people were killed by SARS.

On January 30, the World Health Organization (WHO) declared a global health emergency over the new outbreak.

WHO spokesman Chris Lindmeier warned that closing borders could in fact accelerate its spread, with travelers entering countries unofficially.

“As we know from other scenarios, be it Ebola or other cases, whenever people want to travel, they will. And if the official paths are not opened, they will find unofficial paths,” he said.

He said the best way to track the virus was at official border crossings.

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In a public statement on January 31, Health Secretary Alex Azar said US citizens returning from Hubei province would face 14 days of quarantine while those returning from other parts of China would be allowed to monitor their own condition for a similar period.

He told reporters: “Following the World Health Organization decision, I have today declared that the coronavirus represents a public health emergency in the United States.”

Citing the need to relieve pressure on authorities, Alex Azar said that foreign nationals who had travelled in China in the past two weeks would be denied entry to the US.

He added: “The risk of infection for Americans remains low and with these, and our previous, actions we are working to keep the risk low.”

Another confirmed case in the US on January 31 – in California – brought the number there to seven. Robert Redfield, director of the Centers for Disease Control and Prevention (CDC), said 191 people were under observation for the disease.

The US announcement came as other countries around the world scrambled to contain the spread of the new virus, 2019-nCov.

On January 31, the UK confirmed its first two cases.

Estimates by the University of Hong Kong suggest the true total number of cases could be far higher than official figures suggest. Based on mathematical models of the outbreak, experts there say more than 75,000 people may have been infected in the city of Wuhan alone, where the virus first emerged.

Most cases outside China involve people who have been to Wuhan. Germany, Japan, Vietnam, the US, Thailand and South Korea have reported person-to-person cases – patients being infected by people who had travelled to China.

Meanwhile in Wuhan, voluntary evacuations of hundreds of foreign nationals are under way.

Australia, South Korea, Singapore, New Zealand and the UK are expected to quarantine all evacuees for two weeks to monitor them for symptoms and avoid contagion.