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excess weight gain

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Brown fat produces 300 times more heat than any other organ in the body and stops a baby from freezing to death if left in the cold.

Scientists have discovered that this type of fat is a good thing because it produces lots of heat by burning calories.

Unlike white fat, which clings to our hips and expands our ageing waistlines, brown fat keeps the weight off.

And that’s why the race is on to find out more about brown adipose tissue, also known as brown fat, and how humans could use it to our advantage.

When we’re born we have lots of brown fat in our bodies, wrapped round the central organs to keep us warm, to help us adapt to life outside the womb.

As we grow, however, the brown fat content of our bodies decreases.

Researchers at the University of Nottingham have been using heat-seeking technology to find out if brown fat is still present in children and adults.

Scientists have discovered that brown fat is a good thing because it produces lots of heat by burning calories

Scientists have discovered that brown fat is a good thing because it produces lots of heat by burning calories

Professor Michael Symonds and Dr. Helen Budge from the University’s School of Clinical Sciences say their research, published in the Journal of Pediatrics, shows that the neck region in healthy children produces heat.

“There is only about 50 g of brown fat in the neck region and it switches on and off throughout the day as it’s exposed to different temperatures or if you exercise or eat,” says Prof. Michael Symonds.

But this capacity is much greater in young children compared with adolescents and adults.

He says that the challenge is now to use this knowledge to find out what factors might switch on brown fat, and therefore prevent excess weight gain.

“The more we know about what switches on brown fat the better. It may have an immediate effect which can be retained as you get older.

“This may provide new insights into the role of brown fat in how we balance energy from the food we eat, with the energy our bodies use up.”

Could brown fat have a role to play in fighting obesity too?

It’s a nice theory, says Prof. Sir Stephen Bloom, head of division for diabetes, endocrinology and metabolism at Imperial College London.

“If we activate brown fat, we can eat more and not gain weight. But we would waste energy unnecessarily, we would sweat a lot and forever be opening windows.

“We’d be hot and thin.”

Anything that could mean calories are burned rather than being stored as fat sounds like a good idea – but there are dangers in using agents to activate body tissue.

“Agents have potential for toxicity. It’s great if it works and it’s safe, but everyone is nervous of the side effects of obesity therapies,” Prof. Stephen Bloom says.

Previous research on rodents and small mammals shows that they, like babies, rely on brown fat to keep warm.

“But this might not be so applicable in humans, particularly adults. That much brown fat is not natural in humans.

“It would be hard work to stimulate everything that way.”

Prof. Michael Symonds is more positive, believing that his team’s research using thermal imaging could lead to more useful information on what we eat.

“Potentially we could add a thermogenic index to food labels to show whether that product would increase or decrease heat production within brown fat.

“In other words whether it would speed up or slow down the amount of calories we burn.”

So fat is not as simple as it seems. There are different types and the brown stuff is much better than the white.

But we have no control over the quantities of each kind in our bodies, nor how it is managed.

In the future, Nottingham researchers will look at how nutrition, exercise, and environmental and therapeutic interventions could have an impact on brown fat and its unique heat-generating properties.

In the meantime, Prof. Stephen Bloom says it’s a very promising area to work on.

“It could be a help in the fight against obesity, diabetes and heart problems.”

Are we nearly there yet? “There’s a long way to go. A decade at least.”

The war against white fat is only just beginning.

 

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A British Medical Journal analysis has found that dieting in pregnancy is safe for women and does not carry risks for the baby.

The review looked at the findings from 44 previous studies involving more than 7,000 women.

The London-based team said following a healthy diet – and not eating for two – prevents excess weight gain and cuts the risk of complications.

But current guidelines do not advocate dieting or weight monitoring.

The advice from the National Institute for Health and Clinical Excellence (NICE), published in 2010, says: “Dieting during pregnancy is not recommended as it may harm the health of the unborn child.”

However, women are advised to aim to reach a healthy weight before conceiving.

Half the UK population is either overweight or obese and the rates are rising.

And in Europe and the US, between 20% and 40% of women gain more than the recommended weight during pregnancy.

A British Medical Journal analysis has found that dieting in pregnancy is safe for women and does not carry risks for the baby

A British Medical Journal analysis has found that dieting in pregnancy is safe for women and does not carry risks for the baby

High weights are linked to complications such as pre-eclampsia, diabetes and high blood pressure as well as early delivery.

This review, funded by the National Institute of Health Research (NIHR), compared diet, exercise or a combination of the two.

Dietary advice was based on limiting calorie intake, having a balanced diet and eating foods such as whole grains, fruits, vegetables and pulses.

The researchers then examined how much weight women gained during their pregnancies and if there were complications.

While each approach reduced a woman’s weight gain, diet had the greatest effect with an average reduction of nearly 4 kg (8.8 lbs).

With exercise, the average reduction in weight gain was just 0.7 kg (1.5 lbs). A combination of diet and exercise led to an average reduction of 1 kg (2.2 lbs).

Women following a calorie-controlled diet were significantly less likely to develop each of the complications considered, but the researchers say those findings need to be repeated in larger studies.

Babies’ birth weights were not affected by dieting.

Dr. Shakila Thangaratinam, a consultant obstetrician at Queen Mary, University of London who led the study, said: “We are seeing more and more women who gain excess weight when they are pregnant and we know these women and their babies are at increased risk of complications.

“Weight control is difficult but this study shows that by carefully advising women on weight management methods, especially diet, we can reduce weight gain during pregnancy.

“It also shows that following a controlled diet has the potential to reduce the risk of a number of pregnancy complications.”

She added: “Women may be concerned that dieting during pregnancy could have a negative impact on their babies. This research is reassuring because it showed that dieting is safe and that the baby’s weight isn’t affected.”

But in a commentary in the journal, women’s health experts from St Thomas’ Hospital in London – including Lucilla Poston who helped develop the NICE guidance, said it would be “premature” for the current guidance, which only recommends women be weighed at their first pregnancy check-up, to change.

Dr. Janine Stockdale, research fellow at the Royal College of Midwives, said: “We should be careful to note that the researchers are not advising women to lose weight during pregnancy; this is about managing excessive weight or weight gain.

“If a woman is on target to gain the right amount of weight during her pregnancy, then <<dieting>> and <<calorie-controlled dieting>> as we commonly understand these terms, is not for her.

“We need to reassure women that under the care of a midwife or other health professional, weight management is safe.”