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Selena and Justin – are they breaking up ?

Lisa.Felice
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Selena and Justin – are they breaking up ?

Selena Gomez owns the sold-out audience shouting, singing along out loud, as well as waving paper prints with her name every time she goes on the stage. She’s young and she’s beautiful.

A picture with Justin Bieber performing Justin Timberlake’s “Cry Me a River” makes the tween young ladies go nuts.

[googlead tip=”patrat_mediu” aliniat=”stanga”]  Whilst gossip flow that Justin Bieber and Selena have broken up over a text message Bieber sent to his sweetheart. In a current interview with Contact Music, Gomez stated her romantic relationship with Bieber is actually “all good” although the girl has got zero motives to get married to him.

“No, I’m only 19!” the girl explained when questioned if she will marry the guy someday. Bieber pleasantly surprised admirers, accompanying Selena on stage throughout the girls premier performance on July 25, when he performed Justin Timberlake’s Cry me a River along with his own track, “Favorite Girl”. Soon after, he wrote on tweeter,

“‘Had a great night and surprised the people. felt good to be on stage. nothing is changing that. REAL. @selenagomez u did great tonight. proud of u.”

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Selena Gomez and Justin Bieber
Selena Gomez and Justin Bieber

 

On Thursday, Selena’s boyfriend showed up to support her at the kickoff concert in Boca Raton. But the guy was not on hand on Friday when the girl checked out the actual Wizarding World of Harry Potter at Universal. However, she managed  to enjoy herself lacking him.

She was in fact joined by Ashley Cook, Lindsey Harper as well as Katelyn Clampett as the group sipped on Butterbeer and met the Conductor at Hogwarts Express. They also rode the Hungarian Horntail coaster on Dragon Challenge, which must have been a lot of fun.
Afterwards, Selena tweeted,

“First day off in Harry Potter Land we my girls in Orlando Florida. Having some butter beer. [sic]” 

Apparently, she is taking her time to rest and enjoy herself in between her tour concerts. [googlead tip=”lista_mare” aliniat=”dreapta”]

Let’s not forget about Justin Bieber.  We must ask: What was the reason for choosing “Cry Me a River” out of the many unforgettable and jam-worthy tunes Justin Timberlake has as part of his repertoire? Since you may recall, “Cry Me a River” seemed to be J.T.’s response to his separation with Brit. Perhaps there is something he’s trying to tell Ms. Selena Gomez.
We hope Selena does not go the same way as Brit and Justin.

DB Cooper : Newest updates on his pursuit

Diane A. Wade
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DB Cooper : Newest updates on his pursuit

Following hijacking the aircraft and also requesting ransom two hundred thousand from the Federal bureau of investigation, DB Cooper made a ambitious evade through the use of parachute.

Forty years afterwards, brand new proof suggests the authorities may finally be hot on the path of America’s most mysterious fugitive. Nevertheless what are the latest facts?

DB Cooper
DB Cooper

 [googlead tip=”lista_mare” aliniat=”dreapta”] Around the night before Thanksgiving of 1971, a guy who named himself Dan Cooper (a press reporter being employed by among the many wire assistance misheard the name of the hijacker, and ever since then he has been referred to as D.B. Cooper, as an alternative to Dan) dressed in a suit and raincoat, wandered up to the Northwest Orient desk at Portland’s airport and spent $20 on a one-way ticket to Seattle.

On the flight, he used some dark sunglasses, purchased a whiskey, lit up a cigarette and coolly given the stewardess some text. In capital letters, DB Cooper’s note read:

I HAVE A BOMB IN MY BRIEFCASE. I WILL USE IT IF NECESSARY. I WANT YOU TO SIT NEXT TO ME. YOU ARE BEING HIJACKED.

Just what happened next would give Cooper the place in the pantheon of US folk heroes.  [googlead tip=”patrat_mare”]

D.B. Cooper requested the stewardess to inform the next require to the plane’s captain: he wanted $200,000 and a number of parachutes, and in return, he’d allow 36 people to leave the aircraft as soon as the plane arrived in Seattle. The FBI, swiftly called by ground control, organized the swap, and when the airplane was sky-bound again, with only the pilot, co-pilot, one stewardess and DB Cooper on board. 

The hijacker’s directions were to head for Mexico, keeping an altitude under 10,000 feet. Then, somewhere above the lower Cascade mountains, 25 miles north west of Portland, D.B. Cooper launched the plane’s aft stairs, stepped out, and, with one of the parachutes strapped to his back, jumped into the raining, cold November night and has been never seen or observed from again. [googlead tip=”vertical_mare” aliniat=”dreapta”]

By the moment military helicopters were scrambled, on November 24th 1971, to search the land north of Portland for a six-foot-tall white man weighing one hundred seventy to a hundred seventy five pounds, “DB” Cooper was long gone – most probably possibly dead or packing away his parachute and trudging through mud and rain to make his escape.

Over the previous 40 years since that chilly night, there have been more than 1,000 DB Cooper suspects, a number of deathbed confessions, a film (starring Robert Duvall), as well as well more than a dozen books. As one person told legendary Cooper tracker Alex Hannaford, DB Cooper is the “Bigfoot of the Pacific Northwest.”

Kings of Leon interrupted a concert Friday in Dallas

Sonia Pantiss
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Kings of Leon interrupted a concert Friday in Dallas

Kings of Leon interrupted a concert Friday in Dallas, Texas subsequent to guide performer Caleb Followill informed admirers, “I’m going to move behind the scenes and I’m gonna vomit, I’m gonna drink a beer and I’m gonna come back out and play three more songs.”

The rocker by no means came back to the stage, that pushed the other members of this rock band to say sorry to the viewers. “Caleb’s just a little unfit to play the rest of the show,” explained bassist Jared Followill. “We love you guys so much, but I know you guys fucking hate us. I’m so sorry. It’s really not our fault, it’s Caleb. He can’t play the rest of the show. We will be back as soon as possible.”

Kings of Leon
Kings of Leon

 

 

Even though Caleb Followill has revealed that the cause he quit the stage was because of heat, fatigue and also lack of fluids, his sibling Jared’s remarks on Twitter after the episode suggest that Caleb’s tendencies may be part of a larger issue in the music group. Soon after apologizing again, Jared published “there are internal sicknesses & problems that have needed to be address” and also “I know you guys aren’t stupid. I can’t lie. There are problems in our band bigger than not drinking enough Gatorade.”

This is a common endeavor that other bands are also pursuing. It’s not unusual for singers and other band members to have health problems or other issues which prevent them from singing. Caleb’s problem was health related but we cannot say for sure if that was the only reason for his behavior. 

 

 

 

 

Please view the video below which shows Caleb Followill talking to the audience at the Dallas concert. The video clip also displays footage of the other members of Kings of Leon apologizing him for his sudden departure.

Telomere progressive shortening characterizes familial breast cancer

James J. Williams
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Telomere progressive shortening characterizes familial breast cancer

Prostate cancer: a new treatment option from Swedish Lund University researchers.

 [googlead tip=”patrat_mare” aliniat=”stanga”]

Zelboraf for metastatic melanoma approved by FDA.

 

Potential breakthrough in cancer research: a new treatment for leukemia had amazing results.

 

Hereditary cancer: future methods of diagnosis and treatment

 

Progressive telomere shortening characterizes familial breast cancer patients

Telomere chromosome
Telomere chromosome

 

Telomeres, the complex structures that protect the end of chromosomes, of peripheral blood cells are significantly shorter in patients with familial breast cancer than in the general population. Results of the study carried out by the Human Genetics Group of the Spanish National Cancer Research Centre (CNIO), led by Javier Benitez, to be published in open-access journal PLoS Genetics on July 28th, reflect that familial, but not sporadic, breast cancer cases are characterized by shorter telomeres. Importantly, they also provide evidence for telomere shortening as a mechanism of genetic anticipation, the successively earlier onset of cancer down generations.

Mutations in two DNA repair genes, BRCA1 and BRCA2, characterize some, but not all, instances of hereditary breast cancer. Non-BRCA1/2 breast cancer families are heterogeneous, suggesting the existence of other genes conferring susceptibility. The group has investigated the role of telomere length in hereditary breast cancer based on previous information suggesting, first, that short telomeres and subsequent genomic instability contribute to malignant transformation; second, that genetic anticipation occurs in breast cancer families and, third, that telomere shortening is associated with anticipation in other genetic diseases. [googlead tip=”vertical_mare” aliniat=”stanga”]

By analyzing telomere length differences between mothers and daughters from breast cancer families, the authors demonstrated that genetic anticipation is associated with a decrease in telomere length in affected daughters relative to their mothers.

The results allowed the authors not only to conclude that women carrying BRCA1/2 mutation have chromosomes with short telomeres, but also to describe for the first time that genetic anticipation in breast cancer could be explained by telomere shortening. In addition, the study expands the field of research concerning genetic predisposition to breast cancer to include genes involved in telomere maintenance. The significance of generational changes in telomere length has interesting potential clinical applications in the management of familial breast cancer, and could be extended to other hereditary cancer syndromes.

###

FINANCIAL DISCLOSURE: This work was supported by Asociación Española Contra el Cancer (AECC) and Spanish Fondo de Investigaciones Sanitarias (grant numbers FISPI081298 and FIS-PI081120). The CIBER de Enfermedades Raras is an initiative of the ISCIII. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

COMPETING INTERESTS: The authors have declared that no competing interests exist.

CITATION: Martinez-Delgado B, Yanowsky K, Inglada-Perez L, Domingo S, Urioste M, et al. (2011) Genetic Anticipation Is Associated with Telomere Shortening in Hereditary Breast Cancer. PLoS Genet 7(7): e1002182. doi:10.1371/journal.pgen.1002182

Contact:  
Dr. Beatriz Martinez-Delgado and Dr. Javier Benitez
Spanish National Cancer Research Centre (CNIO)
Human Genetics
Melchor Fernandez Almagro 3
Madrid 28029
SPAIN
[email protected]
[email protected]

Disclaimer  

This press release refers to an upcoming article in PLoS Genetics. The release is provided by journal staff, or by the article authors and/or their institutions. Any opinions expressed in this release or article are the personal views of the journal staff and/or article contributors, and do not necessarily represent the views or policies of PLoS. PLoS expressly disclaims any and all warranties and liability in connection with the information found in the releases and articles and your use of such information.

About PLoS Genetics

 [googlead tip=”lista_medie” aliniat=”stanga”]PLoS Genetics (http://www.plosgenetics.org) reflects the full breadth and interdisciplinary nature of genetics and genomics research by publishing outstanding original contributions in all areas of biology. All works published in PLoS Genetics are open access. Everything is immediately and freely available online throughout the world subject only to the condition that the original authorship and source are properly attributed. Copyright is retained by the authors. The Public Library of Science uses the Creative Commons Attribution License.  [googlead tip=”lista_medie” aliniat=”centrat”]

About the Public Library of Science

The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world’s scientific and medical literature a freely available public resource. For more information, visit http://www.plos.org.

Potential breakthrough in cancer research: a new treatment for leukemia had amazing results.

Vince Young: Young was released and is about to become backup quarterback in Philadelphia.

James J. Williams
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Vince Young: Young was released and is about to become backup quarterback in Philadelphia.

Albert Breer of the NFL Network informs us via twitter that his team has reached an agreement with former Titan Vince Young. This is almost two years to this date, when the Eagles acquired former No. 1 draft pick Michael Vick.

“Looking forward to working with him,” Vick said of Vince Young, via CSNPhilly.com. “We’ll spend a lot of time getting to know one another. It’s cool – I look forward to having him in here, look forward to making him a better player.”

Vince Young
Vince Young
Vince Young might certainly become familiar with a point or two through Vick: Vick offers figured out how to be a trusted passer along with having other-worldly operating ability, and Vick has become a college student of the sport as well as group leader rather than a guy who believes his organic skill means he or she doesn’t need to work hard.

Vince Young, 2006 through 1st game of 2008 before injury and losing job to Collins: 57.3% completions, 6.41 yards per attempt, 22 TD to 32 INT, 6.4% sack rate  

Vince Young, since regaining job in 2009 until incident last year following thumb injury: 59.0% completions, 7.55 yards per attempt, 20 TD to 10 INT, 5.0% sack rate

 

Vince Young | Quarterback   [googlead tip=”patrat_mic” aliniat=”dreapta”]

Team:  Philadelphia Eagles
Ht / Wt:   6’5′ / 232
Age / DOB:   (28) / 5/18/1983
College:  Texas
7/29/2011: Signed a one-year contract.

 

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Wishing good luck to Vince Young in his new position. 

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