Mega Millions confirmed there was one winner for the whopping $1.6 billion prize.
The jackpot numbers were: 28, 70, 5, 62, 65, with a Mega Ball of 5. The odds of choosing those numbers were said to be one in more than 300 million.
Mega Millions was created in 2002 and has seen a number of changes to the rules over the years that have reduced the odds of winning, leading to larger jackpots.
Tickets for the Mega Millions draw are sold in 44 states, the DC and the US Virgin Islands and there had not been a top prize winner since July.
Gordon Medenica, the lead director of Mega Millions Group, said: “The moment we’ve been waiting for finally arrived, and we couldn’t be more excited.
“This is truly a historic occasion. We’re so happy for the winner, and we know the South Carolina Education Lottery can’t wait to meet the lucky ticket holder.”
The winner can decide to take a cash payout of $913 million after tax, or opt to have it paid out in installments over 29 years.
Mega Millions said October 23 draw saw 36 people win second prize, and 419 win the $10,000 third prize.