According to the National Weather Service (NWS), a “potentially historic blizzard” could dump up to 3ft of snow on the north-east coast.
New York’s mayor said the storm could be the city’s biggest ever, telling residents to “prepare for the worst”.
Heavy snowfall is forecast from Philadelphia to Maine. More than 3,000 flights have already been cancelled.
A blizzard warning has been issued for New York and Boston from Monday afternoon until Tuesday.
More than 1,800 flights on January 26 and more than 1,600 on January 27 had been cancelled, according to the website FlightAware.
Photo Reuters
Airports in New York, Boston and Philadelphia have already been affected.
NYC Mayor Bill de Blasio showed journalists a list of the city’s top 10 snowstorms, dating back to 1872.
“This could be the biggest snowstorm in the history of this city,” Bill de Blasio said, telling New Yorkers to “prepare for something worse than we have seen before”.
“Prepare to be safe, take every precaution. Now is the time to get ready for this extreme weather.”
Some residents have already begun stocking up on food, water and other essential items.
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A massive snowstorm made seven victims in New York state on November 19 as another 3ft of snow is expected to hit parts of north-eastern US.
Weather-related deaths were also reported in New Hampshire and Michigan.
Parts of the city of Buffalo are already under 5ft of snow. New York Governor Andrew Cuomo called the snowstorm a “historic event”.
Freezing temperatures have continued in many parts of the US, with heavy disruption to travel.
Weather related deaths were also reported in New Hampshire and Michigan.
Residents were reported trapped in their homes and cars, and strong winds and icy roads caused motorway accidents and forced school closures in parts of the US.
More than 100 National Guard members were deployed in New York to assist in clearing roads and removing abandoned vehicles.
The National Weather Service said some places could have topped the record for a single day of snowfall, which stands at 6ft 4in.
Train services in parts of New York state were suspended on November 19, while long stretches of road near Buffalo were closed.
As well as the fatalities in New York, there were two other weather-related deaths reported in New Hampshire and Michigan.
About 20 people have died across the US since November 15.
Three firefighters in Indiana were also injured when a trailer struck a fire truck on a snow-covered road.
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The New York snowstorm has killed at least five people after dumping 5ft of snow in parts of the state.
The city of Buffalo was forecast to get 6ft later on November 19 with another storm due to wreak more chaos.
The storm was blamed for five deaths in New York state – one in a car crash, one trapped in a car and three from heart attacks.
Temperatures across all 50 US states plummeted to freezing, and there were several snow-related deaths elsewhere.
Residents were reported trapped in their homes and cars, and strong winds and icy roads caused motorway accidents and forced school closures in parts of the US.
A women’s basketball team from Niagara University was left stranded on a roadway for hours before being picked up by authorities.
New York Governor Andrew Cuomo deployed more than 100 National Guard members to assist in clearing roads and removing abandoned vehicles.
The National Weather Service said some places could top the record for a single-day of snowfall, which is 6ft 4ins.
Train service in parts of New York state was suspended on November 19, while long stretches of highway near Buffalo were shuttered.
As well as the fatalities in New York, there were two other weather-related deaths reported in New Hampshire and Michigan.
About 20 people have died across the US since November 15.
Three firefighters in Indiana were also injured when a trailer struck a fire truck on a snow-covered roadway.
Amid the weather, the State University of New York Buffalo announced it planned to go ahead with a nationally televised football game on Wednesday evening, although all pre-game activities were cancelled.
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