Jennifer Aniston and Chelsea Handler have been known as being the best friends, with Jennifer saying: “I am madly in love with Chelsea Handler.”

What appears to be roses and champagne on the surface hides murkier depths, if a segment filmed for Chelsea Handler’s After Lately show is anything to go by.

In the show, Chelsea Handler, 36, proudly introduces her A-list friend Jennifer Aniston to her E! writing team and tells them that the former Friends star was tickled by a sketch they’re working on.

But when Chelsea Handler has to take a call, Jennifer Aniston asks the team: “Do you think that’s funny? That is so not funny.”

The Chelsea Lately writers agree that the humour is off but defend their star by telling her friend that she’s been very busy.

Then Jennifer Aniston really hits her stride, by asking sarcastically: “[Is she busy] gossiping about more successful people that are better-looking than her? Putting her name on another dumb book to make the world an even dumber place?”

Then Jennifer Aniston sardonically drawled: “<<Hi, I’m Chelsea. I really think that everything I say is funny>>. You know what I mean? It’s a shock that she really still has her own show.”

Before asking: “That little guy…?”

To which the team chime together: “Chewy,” referencing Chelsea Handler’s sidekick and comedy foil on the show.

In the After Lately show, Chelsea Handler proudly introduces her friend Jennifer Aniston to her E! writing team and tells them that she was tickled by a sketch they're working on

But Jennifer Aniston lampoons Joan Rivers’s recent condemnation of Chelsea Handler, by saying: “No, the little one that she slept with to get the gig? He doesn’t even work for the network anymore.”

Jennifer Aniston went on to claim that Chelsea Handler is not the cleanest person, adding: “And then her hygiene… have you noticed this? Honestly, when we were in Cabo, she never showered! She would be like, <<What? I went in the pool>>. It’s gross!”

Of course, it’s all for fun and Jennifer Aniston, who was recently reported to be expecting her first child with boyfriend Justin Theroux, is still besotted with her gal pal.

Staff writer, Heather McDonald told US Weekly: “It was great having Jen Aniston on the show. She’s super sweet, has a really hot body, the good hair.

“Jen is also a good-friend to host Chelsea, as she had no problem doing her friend a favour and making an appearance.”

Reese Witherspoon was another actress who was given a good report by the writer after she made her second cameo on the show.

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