Just one day after eating her words against rapper Drake on Twitter, Amanda Bynes is back on the offensive.

Amanda Bynes, 27, spent much of the day calling random followers ugly, telling them she doesn’t care about them and lodging threats those she believes to be enemies, like: “If I don’t like you I don’t want you to be happy and I’ll go out of my way to hurt you” and “If you steal from me you’ll pay a price.”

However, when actor Jason Biggs finally weighed in on Amanda Bynes’ ramblings, the insults started flying again.

It all began when Amanda Bynes wrote: “If you’re not hot I don’t care about you.”

Amanda Bynes labels American Pie actor Jason Biggs ugly in her latest string of bizarre Twitter attacks

The American Pie star responded to her random tweet with: “This self-hatred really must stop, Amanda.”

To which Amanda Bynes retorted: “@JasonBiggs you’re so ugly I won’t talk to you.”

Shortly thereafter amanda Bynes ramble-tweeted: “You get turned on but what you are not by what you’re not.”

To which Jason Biggs responded again with this hilarious tweet: “Are you having a stroke?”

However, Amanda Bynes didn’t find it funny, responding both to Jason Biggs and another follower who had apparently crossed her with: “@TwitFlickR @JasonBiggs what a joke you both are good luck getting laid by anything with a vagina.”

Then celebrity therapist Dr. Drew Pinsky weighed in on Amanda Bynes’ condition: “I think it may be time to leave @AmandaBynes alone. She will get help if she wants it & if she needs it, hopefully before serious consequences.”

Not surprisingly, Amanda Bynes responded in her usual, childish way: “@drdrew WHAT ARE YOU TALKING ABOUT? What kind of help are you referring to? You’re ugly and I want you to leave me alone!”