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Michelle Obama has released a memoir in which she reveals that she had a miscarriage and used in vitro fertilization to conceive both children, Malia and Sasha.

In the book, Becoming, the former first lady reveals difficulties about her marriage and pregnancy with her two daughters.

In an interview with ABC’s Good Morning America, Michelle Obama said that she felt “lost and alone” after her miscarriage 20 years ago.

The first African-American first lady also criticized President Donald Trump for putting her family’s safety at risk.

Michelle and Barack Obama sought couples therapy, she also revealed for the first time in her 426-page book, which will be released on November 13.

Following publication, Michelle Obama will tour ten cities.

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Michelle Obama, a former lawyer and hospital administrator, told ABC that after her miscarriage: “I felt like I failed because I didn’t know how common miscarriages were because we don’t talk about them.”

She added that “it’s important to talk to young mothers about the fact that miscarriages happen”.

The former first lady also said that when she was around 34 years old, she realized that “the biological clock is real” and that “egg production is limited”, which made her decide to seek in-vitro fertilization.

She told Robin Roberts: “I think it’s the worst thing that we do to each other as women, not share the truth about our bodies and how they work.”

Michelle Obama revealed that the couple’s relationship struggled at times, especially after her husband joined the state legislature, leaving her at home where she was forced to administer IVF shots herself.

“Marriage counseling for us was one of those ways where we learned how to talk out our differences,” she said.

“I know too many young couples who struggle and think that somehow there’s something wrong with them. And I want them to know that Michelle and Barack Obama, who have a phenomenal marriage and who love each other, we work on our marriage.

“And we get help with our marriage when we need it.”

Michelle Obama also describes falling in love with the former president one summer night in Chicago.

In Becoming, Michelle Obama says she would “never forgive” Donald Trump for championing the “birther” theory that her husband was not born in the US, according to excerpts obtained by media.

She wrote: “The whole [birther] thing was crazy and mean-spirited, of course, its underlying bigotry and xenophobia hardly concealed.”

“What if someone with an unstable mind loaded a gun and drove to Washington? What if that person went looking for our girls? Donald Trump, with his loud and reckless innuendos, was putting my family’s safety at risk. And for this I’d never forgive him.”

Michelle Obama said she reacted in shock to Donald Trump’s presidential victory and “tried to block it all out”.

Before departing the White House for Paris on November 9, President Trump addressed some of the quotes from Michelle Obama’s book.

He said: “Michelle Obama got paid a lot of money to write a book and they always insist you come up with controversy. I’ll give you some back.”

Referring to his predecessor, Barack Obama, President Trump said: “I’ll never forgive him for what he did to our United States military by not funding it properly.”

First ever IVF puppies have been born to a surrogate mother after years of attempts, say scientists at Cornell University in New York.

The IVF success paves the way for conserving endangered breeds and could help in the fight against human and animal diseases, say researchers.

The seven beagle and cross-bred beagle-spaniel puppies were born to a surrogate mother.

They were from the same litter but have three sets of parents.

Frozen embryos were implanted in a female dog using techniques similar to those used in human fertility clinics.

Photo Cornell University

Photo Cornell University

Problems with freezing embryos have caused difficulties in the past, but the researchers say they have perfected this and other techniques.

Lead researcher Dr. Alex Travis, from Cornell’s college of veterinary medicine, said: “We have seven normal happy healthy puppies.”

He added: “Since the mid-1970s, people have been trying to do this in a dog and have been unsuccessful.

“Now we can use this technique to conserve the genetics of endangered species.”

The researchers say IVF (in vitro fertilization) is a powerful tool to help endangered species of dog such as the African wild dog.

It could also be used in the study of inherited human and dog diseases.

Dogs share many similar diseases with humans – almost twice as many as for any other species.

Dr. Alex Travis said the work was an important milestone.

The puppies were born on July 10, but their existence was kept secret until the findings were formally announced to the scientific world this week.

They have reportedly been named Ivy, Cannon, Beaker, Buddy, Nelly, Red and Green, and all but one has gone to a new home.

The research, published in the journal PLoS One, has been described as a “major step forward” in medicine.