DSM-5, the latest psychiatrist bible, is warning of the dangerous physiological impact of caffeine intoxication.

An overdose of caffeine is among the mental disorders included in the latest edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) released on May 22.

Symptoms of the disorder include restlessness, nervousness, excitement, red face, gastrointestinal upset, muscle twitching, rambling speech, sleeplessness, rapid and irregular heartbeat, according to Live Science.

The findings about the mental impacts of a caffeine overdose come from the list of mental disorders compiled by the American Psychiatric Association (APA).

The DSM is the go-to guide for a myriad of professionals seeking to understand mental disorders including physicians, psychologists, social workers, nurses, occupational and rehabilitation therapists, and counselors, according to the APA website.

DSM-5 is warning of the dangerous physiological impact of caffeine intoxication

Caffeine intoxication had previously been listed as a disorder but in the latest edition of the DSM, it also includes the disorder associated with caffeine withdrawal.

Symptoms of caffeine withdrawal are described as including headache, fatigue, difficulty concentrating, depressed mood and other issues.

“Caffeine is invading our society more and more,” Alan Budney, who served on the DSM-5 working group for substance-use disorders, previously told Medscape Medical News in 2011 about why caffeine withdrawal was an important disorder to investigate.

“There’s concern enough to consider this topic seriously, even though it’s probably one of the more controversial issues faced by our work group,” he added.

Caffeine is considered the most widely used, behaviorally active drug in the world, alongside other chemicals that can prompt mental disorders.

The other powerful chemicals include alcohol, nicotine, cannabis, hallucinogens and other mind-altering substances.