The Nobel Prize in Chemistry 2013 was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel “for the development of multiscale models for complex chemical systems”.
The three scientists “took the chemical experiment into cyberspace”.
Michael Levitt, a British-US citizen of Stanford University; US-Austrian Martin Karplus of Strasbourg University; and US-Israeli Arieh Warshel of the University of Southern California will share the prize.
The trio devised computer simulations to understand chemical processes.
In doing so, they laid the foundations for new kinds of pharmaceuticals.
“The Nobel Laureates in Chemistry 2013 have made it possible to map the mysterious ways of chemistry by using computers,” said the Royal Swedish Academy of Sciences.
“Today the computer is just as important a tool for chemists as the test tube.
“Detailed knowledge of chemical processes makes it possible to optimize catalysts, drugs and solar cells.”
Arieh Warshel told a news conference in Stockholm by telephone that he was “extremely happy” to be woken in the middle of the night in Los Angeles to find out he had won the prize.
“In short, what we developed is a way for computers to take the structure of a protein and then to eventually understand how exactly it does what it does,” he told reporters.
Marinda Li Wu, president of the American Chemical Society, said the award was “very exciting”.
“The winners have laid the groundwork for linking classic experimental science with theoretical science through computer models.
“The resulting insights are helping us develop new medicines; for example, their work is being used to determine how a drug could interact with a protein in the body to treat disease.”