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ageing process


According to new research, staying youthful for longer could be within your reach thanks to a daily vitamin pill – Imedeen’s Time Perfection.

Lots of the most beautiful celebrities already credit their perfect skin to Imedeen’s Time Perfection youth pills including models Naomi Campbell, Helena Christensen and Laura Bailey, actress Jessica Biel and Danni Minogue.

And women looking for an anti-ageing solution don’t have to take their word for it, a new study conducted in Brazil has revealed that daily use of the supplements can help slow down the ageing process by as much as 48%.

The study, undertaken by Brazilian cosmetic dermatologist, Dr. Adilson Costa – head of the Dermatology Department, Pontifical Catholic University of Campinas in São Paolo – followed a test group of women taking the daily pill aged between 35 and 60 over a period of 12 months.

The results revealed a 30% reduction in fine lines and a similar decrease in wrinkles. Radiance and smoothness were also boosted by a huge 42%.

According to new research, staying youthful for longer could be within your reach thanks to daily vitamin pill Imedeen's Time Perfection

According to new research, staying youthful for longer could be within your reach thanks to daily vitamin pill Imedeen’s Time Perfection

Ingredients in the Time Perfection supplement include a mega dose of anti-oxidant vitamin C, zinc and a substance called lycopene, which is extracted from the skin of tomatoes.

The latter was the subject of a study by L’Oreal a few years ago, which found that it had a marked effect on ageing.

A-list fans such as Jessica Biel have talked of their love for the supplements in the past, which they describe as the reason for their preternaturally youthful skin.

The new Mrs. Timberlake revealed that she believes skin is a ‘reflection of your inner health’ in a recent interview with website, Yahoo.

Jessica Biel is famed for her glowing complexion and credits a combination of facials, skincare and supplements for keeping it in good shape.

“Your skin is a reflection of your inner health, so I try to eat well, stay hydrated and get regular exercise,” she explained.

“I also have monthly facials, which are a combination of natural fruit peels and massage. Plus I take Imedeen skin supplements.”

Model Naomi Campbell also spoke of her faith in Imedeen’s anti-ageing prowess.

“My beauty secret [is that] I use Creme de la Mer and I take Imedeen so my skin always has an air of good health,” she revealed.

Meanwhile, 42-year-old supermodel Helena Christensen has admitted to using another beauty pill in preparation for time on the beach.

Imedeen’s Tan Optimizer pill is part of the brand’s anti-ageing range and helps protect skin from sun damage.

“I tan easily and as everyone, I wish to preserve my suntan as long as possible,” said the Danish model.

“ImedeenTan Optimizer is a very healthy partner.”


Doctors have discovered why wounds such as ulcers take longer to heal in older people – and they believe a cream containing the female hormone oestrogen could be the answer.

Diabetics, the elderly and people with nerve damage or circulatory problems are particularly at risk.

Not only are these wounds painful and debilitating – taking months to heal or, in some cases, never healing – they also leave people exposed to potentially life-threatening infections because there is no barrier preventing bacteria entering the body.

Furthermore, research shows that patients who develop a non-healing wound end up staying in hospital three times longer than they should.

Until now, it has been poorly understood why some wounds take a long time to heal.

It’s thought it is because cells are not co-ordinating properly to allow tissue to heal, although the precise mechanism is not known.

This means current treatments – including dressings and even the use of maggots to clean wounds – are largely ineffective.

For some, the only solution is amputation.

Now British researchers at the University of Manchester have discovered that the female hormone oestrogen – which is naturally present in both men and women – plays a key role in wound healing.

Oestrogen levels decline in both men and women as they get older as part of the natural ageing process: in women after the menopause while men experience a gradual fall from their 20s.

Falling oestrogen levels are known to age the skin, reducing elasticity and altering the body’s response to inflammation.

Laboratory tests have now shown that oestrogen has an effect on a range of different cells within a wound.

The research involved taking tissue samples from young and older men and looking for differences in the genes involved in the body’s healing process.

Scientists found the main variations were in genes affected by oestrogen.

The differences in the genes were “very strong” between the young and older men, explains Dr. Matthew Hardman, a senior research fellow from the University of Manchester’s Healing Foundation Centre who made the breakthrough.

In other words, the natural fall in oestrogen levels that occurs with age is the reason wounds don’t heal as well in older people. This led to the conclusion that if older people could be given oestrogen, their bodies would heal better.

Dr. Matthew Hardman says: “We knew that oestrogen was important in healing, but we didn’t realize it played such a pivotal role.

“Our discovery could lead to a new treatment for people with non-healing wounds.

“This could make a huge difference to their lives, as these wounds are not only painful but cause immobility and social isolation.”

However, it is not possible to simply give patients oestrogen because of its side-effects, including an increased risk of cancer, he adds.

“So we have been developing and testing treatment options using compounds similar to oestrogen but without the side-effects that come with it.”

Breast cancer drug Tamoxifen, which is similar in structure to oestrogen, has been identified as a possible treatment for non-healing wounds by the researchers.

After successfully turning the drug into a cream that can be applied to an open wound, they are about to test it on 30 volunteers over the age of 65.

They will receive two small skin cuts, one treated with the Tamoxifen cream and the other with a placebo.

If the trial is successful, the cream will then be tested on a larger group of patients with chronic wounds and could be widely available in five years’ time, says Dr. Matthew Hardman.

Meanwhile, researchers have been testing the benefits of algae for slowing down the effects of ageing.

A study published in the journal Actia Biochmica Polonica shows that an antioxidant harvested from sea algae may improve skin elasticity and moisture content.

In one trial, conducted in Japan, 30 women with dry skin were given a 6mg daily oral supplement and a rub-on solution.

After eight weeks there were significant improvements in moisture content of the outer skin layer.

In another trial with 36 men, moisture content and sebum oil level in the cheeks improved after six weeks.

It’s thought the benefits may be due to the antioxidant astaxanthin, also found in fish and seafood (it provides the red color of salmon).

This may help protect the outer layers of the skin against free radical cell damage.


A new research found that stem cells can halt ageing and even prolong lifespans up to three times. An experiment of University of Pittsburgh scientists proved that a single injection of stem cells could make mice live three times as long.

The injection also made the mice grow bigger and stronger.

Scientists think that studying the proteins within stem cells might hold the key to injections that offer a “shot of youthful vigour” to human beings.

The researchers say further research could help us hold off the ageing process altogether.

The effect was even visible on cells in a lab dish where young stem cells were placed next to prematurely ageing cells.

The sick, ageing cells performed better after being placed next to the healthy ones.

The researchers conducted experiments on mice modified to age prematurely, a condition known as progeria.

Progeria also occurs in humans.

Giving these mice shots of stem cells from young, healthy counterparts allowed them to live up to three times longer than those with progeria.

Their experiment saw them first study the stem cells of the progeria sufferers.

The scientists saw there was a difference between the cells in the mice with the ageing disorder – they had fewer, the ones they had regenerated less quickly than ordinary mouse stem cells.

However, injecting stem cells into 17 day-old mice saw a huge increase in their lifespans – from an average of just 21-28 days to more than 66 days, three times longer than usual.

The modified mice given stem cell shots grew almost as large as their healthy counterparts and grew new blood vessels in their brains and muscles.

Scientists think this is because the healthy stem cells helped correct abnormalities in the cells of the rapidly-ageing mice.

Study author Dr. Laura Niedernhofer, whose findings were published in journal Nature Communications said: “Our experiments showed that mice that have progeria, a disorder of premature aging, were healthier and lived longer after an injection of stem cells from young, healthy animals.”

“That tells us that stem cell dysfunction is a cause of the changes we see with aging.”

Dr. Laura Niedernhofer added: “As the progeria mice age, they lose muscle mass in their hind limbs, hunch over, tremble, and move slowly and awkwardly.

“Affected mice that got a shot of stem cells just before showing the first signs of ageing were more like normal mice, and they grew almost as large.

“Closer examination showed new blood vessel growth in the brain and muscle, even though the stem/progenitor cells weren’t detected in those tissues.

“In fact, the cells didn’t migrate to any particular tissue after injection into the abdomen.

“This leads us to think that healthy cells secrete factors to create an environment that help correct the dysfunction present in the native stem cell population and aged tissue.

“In a culture dish experiment, we put young stem cells close to, but not touching, progeria stem cells and the unhealthy cells functionally improved.”