A Tennessee ticket had the winning numbers for a $421 million Powerball jackpot, officials said after November 26 draw.
The winning numbers were 17, 19, 21, 37, 44, with the Powerball 16. No one as yet had stepped forward to claim the prize.
The Powerball prize grew in size since September 17, the last time anyone matched all six numbers.
The jackpot soared from $403 million to a reported $420.9 million on November 26 due to a spate of late ticket-buying.
The prize is paid out over 30 years, with the option of a lump sum payment, which officials said would add up to about $254.7 million.
The odds of winning the Powerball jackpot are 1 in 292 million.
The largest ever US lottery prize of $1.6 billion was split between three winning tickets in January.
Powerball is played in 44 states, the District of Columbia, Puerto Rico and the US Virgin Islands. Players can either buy $2 tickets using their own numbers or have them randomly generated by a computer.