Comedian John Pinette has been found dead in a hotel room in Pittsburgh, Pennsylvania, aged 50.
John Pinette died of natural causes, the local medical examiner’s office told Associated Press.
A veteran of the international comedy circuit, John Pinette was also famous for his role in the final episode of the sitcom Seinfeld.
The actor had just started a tour across venues in the US and Canada, which was due to finish in June.
John Pinette died at the Sheraton Station Square Hotel in Pittsburgh on Saturday afternoon, US media report.
A spokesperson for the medical examiner’s office said John Pinette had been suffering from liver and heart disease. His manager told the Hollywood Reporter the actor had suffered a pulmonary embolism.
John Pinette was born in Boston in the state of Massachusetts in 1964 and was given his break when he was asked to tour with Frank Sinatra.
In his Seinfeld appearance, John Pinette played the role of a carjacking victim mocked by the stars of the show, who in turn end up before a judge for failing to help him.
John Pinette was known for making self-deprecating jokes about his weight and his agent, Nick Nuciforo, told US media he had been working on a stand-up project when he died.
His film credits included an appearance alongside John Travolta in The Punisher in 2004.
John Pinette also performed on Broadway and was a regular guest on NBC’s long-running The Tonight Show.
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