Justin Bieber won best male, best North American act, best collaboration for Where Are You Now?, with Skrillex and Diplo, biggest fans and best look.
Accepting his best male award, Justin Bieber said: “It’s been a long couple of years, um, I just feel like this is pretty awesome to be recognized for my music.”
He has had a number of legal run-ins, including being arrested last year on suspicion of driving under the influence.
One Direction won the prize for best pop, Taylor Swift’s Bad Blood won best song and Rihanna was named best female.
Ed Sheeran hosted the ceremony at Mediolanum Forum in Milan on October 25 – and took home the prize for best live act.
He also won the best world stage award for his performance at last year’s V Festival.
Duran Duran members were honored with the inaugural MTV Video Visionary Award.
“When we started there was us and MTV and we blazed a trail and we were there for each other,” said Simon Le Bon as he collected the award.
A surprise winner in the best video category was hip-hop duo Macklemore and Ryan Lewis.
“I had no idea we were going to win an award,” said Macklemore.
“We’re not on a major label; we don’t have a big budget. What you guys give to us, we give back to you in the art we make.”
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