The German school class was on its way back from an exchange trip.
The Airbus A320 – flight 4U 9525 – went down between Digne and Barcelonnette. None of the 144 passengers or six crew is expected to have survived.
The plane crashed after an eight-minute descent, an official said. It is not clear if it sent a distress signal.
A rescue helicopter has reportedly reached the site of the crash, in a remote mountain area.
Gilbert Sauvan, a local council official, told Les Echos newspaper that the plane had “disintegrated”.
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