Robert Downey Jr. and Robert Duvall legal drama The Judge will officially kick off the 10-day event.
The 39th annual Toronto International Film Festival is currently being held from September 4 to 14.
Both stars are expected to grace the red carpet for the gala at Toronto’s Roy Thompson Hall.
Some 300 films will be screened at the festival, including Alan Turing movie The Imitation Game and Stephen Hawking biopic The Theory of Everything.
Al Pacino film The Humbling – based on Philip Roth’s final novel – will also premiere on September 4.
The Oscar-winner was honored at the festival’s charity gala , with a Q&A looking back over his career.
King Street, on which the festival’s main headquarters is situated, has been closed to traffic and streetcars to enable the public to get closer to the red carpet action.
Other films set to premiere include a big screen version of the 1980s TV series The Equalizer starring Denzel Washington, Michael Douglas thriller The Reach and Ethan Hawke drone drama Good Kill.
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