In addition, it has quarantined an area of the capital Monrovia.
President Ellen Johnson Sirleaf said the curfew would be from 21:00 to 06:00 local time.
She said all movement would be blocked in and out of the West Point area.
Meanwhile, three doctors with Ebola who started taking experimental drug ZMapp last week showed remarkable signs of improvement, a Liberian minister said.
Information Minister Lewis Brown said the drug was given to one Nigerian and two Liberian doctors who had caught Ebola while helping to save the lives of other victims of the virus.
In a radio broadcast, the Ellen Johnson Sirleaf blamed her government’s failure to bring Ebola under control on the public’s disregard for the advice of health workers and disrespect for official warnings.
Liberia already imposed a state of emergency earlier this month, but the number of deaths from the disease has continued to climb.
A mob attacked a health centre in West Point on Saturday, during which 17 suspected Ebola patients went missing.
Ebola has no known cure but the World Health Organization (WHO) has ruled that untested drugs can be used in light of the scale of outbreak in West Africa.
Since the beginning of the year, 1,229 people have died of the virus.
It is transmitted by direct contact with the body fluids of an infected person.
Initial flu-like symptoms can lead to external haemorrhaging from areas such as eyes and gums, and internal bleeding which can cause organ failure.
Ebola outbreak began in Guinea and has since spread to Liberia, Sierra Leone and Nigeria.
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