Lindsay Lohan told the New York Times last week she had been in London preparing for a potential role and was “nervous but excited”.
David Mamet’s play, which first opened on Broadway in 1988 starring Madonna, satirizes the Hollywood film industry.
It will run at the Playhouse Theatre from September 24 to November 29.
Lindsay Lohan will play the role of Karen, a temporary secretary who puts the relationship of two Hollywood producers under strain.
It will be directed by Lindsay Posner, who previously directed other David Mamet plays including Oleanna and A Life in the Theatre.
The West End production is being brought to the stage by Theatre Royal Bath, which was also behind recent West End productions Relative Values, Relatively Speaking and Fences.
Further casting will be announced later.
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