The blast hit Urumqi’s south railway station on Wednesday evening, state media said. The cause is not clear, but one report said at least 50 were hurt.
Xinjiang has experienced several violent clashes over the past months.
President Xi Jinping visited the region this week, and has promised to step up anti-terrorism efforts.
Verifying reports from the region is difficult because the information flow out of Xinjiang is tightly controlled.
“A blast occurred at Xinjiang’s Urumqi train station at around 19.00 tonight, and there are injured personnel,” state-run newspaper People’s Daily said on its verified microblog feed.
Meanwhile, The Beijing News said at least 50 people had been injured, citing police officers.
Photos on social media, which could not be independently verified, appeared to show suitcases and debris strewn across a street after the blast.
However, several microblog posts and photos related to the explosion appeared to have been quickly deleted from Sina Weibo, China’s largest microblog platform.
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